It's 1978 and the ever-ordinary Ave Maria Mulligan (Ashley Judd) leads a simple life. She lives with her mother, runs the pharmacy, directs The Trail of the Lonesome Pine Outdoor Drama, and hopes that her best friend will take their platonic friendship in a romantic direction. Ave Maria waits, and before she knows it, she turns 40. Now the old maid of Big Stone Gap, Ave Maria decides that happiness is for other people - that is, until a long-buried family secret throws her quiet life spectacularly off course. With an all-star cast, Big Stone Gap is a love letter to small-town life, working people and the triumph of love.