As a virulent plague wreaks havoc on the world, a pugnacious young man (Chris Pine) and his more sensitive, intellectual brother (Lou Taylor Pucci) undertake a dangerous trek across the American Southwest. Though they hope to safely escort two women (Piper Perabo, Emily VanCamp) to a resort they know from childhood, threats of disease and violence loom closer with every step they take. Grim chiller co-stars Christopher Meloni, Kiernan Shipka. 84 min. Widescreen (Enhanced); Soundtracks: English Dolby Digital 5.1, Spanish Dolby Digital 5.1; Subtitles: English, French, Spanish.