Arthur Dichter thinks he's dying of insomnia, but the reality is much more frightening. He wanders the streets, finding new ways to keep his body moving, even self-mutilation. His doctors wonder if he's suicidal. His wife, Anna, denies it, knowing he is in a waking nightmare where delusions and reality become more and more indistinguishable. As his disease gives way to despair, loneliness, and alienation, he and his wife try to hang on to their last shred of hope until the bitter end.