Brilliant scientist Sebastian Caine (Kevin Bacon) has one passion: To uncover the secrets of invisibility. Working with his research team in a top-secret government facility, Caine will stop at nothing to achieve his goal, even if it means making himself the project's first human guinea pig. But Caine and his team soon find out that making someone invisible is the easy part - it's keeping him sane that's difficult. Now Caine is a killer on the loose and his team, led by ex-girlfriend Linda (Elisabeth Shue) and her new beau Matt (Josh Brolin), must destroy him. But how do you stop something - or someone - you can't see?